![]() Increased understanding of the array of methods for individual tests and the ways best to interpret result for each test can be critical in optimizing decisions for patient care. These can be in the form of medical practitioner consults, allied health input, medications, dialysis, and biochemical monitoring of progression and complications.īiochemical tests are pivotal to the diagnosis, monitoring, and management of CKD. ![]() In the healthcare setting, many resources are allocated toward the monitoring and treatment of CKD. It is a condition associated with long-term morbidity and mortality linked to its severe impact on the cardiovascular system. Finally, pitfalls of the primary methodologies for the above tests are provided to guide readers in better understanding the results and their use in patient care decisions.Ĭhronic kidney disease (CKD) is a significant health issue, with a global prevalence approaching 10%. There are several other markers discussed in brief that may be a useful adjunct in identifying causes and likely management strategies for CKD. Urinary protein estimate’s use is declining, especially 24-hour collections. Globally, urinary albumin and albumin-creatinine ratio are the recommended tests from a spot collection to estimate the kidney damage. Alternatively, exogenous markers that can be used include inulin, iotalamat, and iohexol if clarity is not achieved with creatinine or cystatin C. Less frequently used endogenous marker for estimating the GFR is cystatin C. For diagnosing CKD, the GFR needs to be <60 mL/min/1.73 m 2 for more than 3 months. The primary biochemical markers for the diagnosing and evaluating stages of chronic kidney disease (CKD) are serum creatinine and the estimated glomerular filtration rate (GFR).
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